An Evolutionary Irony

Football scholarship, or Army?

Should I take the Football scholarship, or the Army contract with the bonus?

What it Neanderthals did not die out due to competition with humans, or lack of resources, or change of climate? What if they died out because of a disease they couldn’t cope with? A virus that just happened to crop up at the right time, and that humans had immunity to – or at least relative resistance – and Neanderthals did not.

I suggest this thought only for the love of irony, as a molecular geneticist named Professor George Church at Harvard seeks to find a woman willing to give birth to a Neanderthal. No, this isn’t a joke. Yes, he can probably do it – to an extent. I’m not sure if we have all the pieces of the Neanderthal genome, but the Professor thinks we do, and it’s his technology.  He developed MAGE – Multiplex automated genomic engineering – a method for using broken DNA as a template for reconstructing a complete genome from pieces. See the link above for a description of the process if you’re interested.

If he finds a willing woman – which seems quite likely given the number of individuals on the planet and the diversity of personalities should statistically give rise to one willing to take this risk – then it’s quite possible he shall succeed in his attempt. And, as he points out, if Neanderthals are healthy, strong and smart, then many people may want to have them. Who knows, it could start a trend.

But what if they’re smarter and stronger than us, and they’re also far more aggressive? How ironic would it be that a quirk of nature at the wrong time wiped them out, only to have them reconstituted by their weaker counterparts – humans – and then they supplant us, coming to dominate the world once more? It is a delicious irony, worthy of a science fiction novel similar to Jurassic Park, but instead of dinosaurs, it would be Neanderthals. And there would be no park. Too bad Michael Crichton isn’t still alive. This would be a perfect project for him.

Neanderthal2Given the bioethical ramifications of what Professor Church is proposing, I’m surprised there isn’t more push-back in regards to this concept. I would think germ-line genetic modifications of this nature would be illegal, and fall under human experimentation. But, perhaps there is no law restricting him from attempting this. Or perhaps he has chosen to ignore it. I can’t say. Moreover, I doubt such a project would lead to Neanderthals dominating humanity. It is highly unlikely given the number of us that currently exist on the planet. But I can’t help but think of the irony, simply because it makes such a wonderful story. Destroyed by nature and reborn by their successors, how would Neanderthals perceive themselves in our world? Could they compete with us? Would they come to dominate the world of sports? Would the NFL restrict them from football? Would the military seek to recruit them for use as infantry? Would religious organizations label them abominations? Would they seek to band together in racial segregation, or integrate happily with their fellow sapiens?

And if we could do this, would we stop at Neanderthals? What about other hominids? What about other creatures? The Professor has proposed bringing back mammoths, and is ready to do so using elephant DNA as a template in the MAGE process. Any extinct critter we’ve got at least some DNA remnants for is a suitable subject. How about the Quagga, a half zebra half horse extinct since 1883? How about the Tasmanian Tiger, extinct since 1936? How about Stellar’s Sea Cow, extinct since 1768? How about the largest deer, the Irish Deer, that vanished 7,700 years ago? How about the Caspian Tiger, extinct since 1970? Or Aurochs, a type of large cattle extinct since 1627? The Dodo, the Cave Lion, the Great Auk, all of which vanished while humans walked the earth. If we can reconstitute Neanderthals via humans, then why not these? We have zebras, horses, tigers, manatees, deer, all of which could be used to gestate the modified germ cells, so why even start with humans?

Neanderthal3

Thanks for reconstituting my genome, biotches.

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7 Responses

  1. Wasn’t this planet of the apes?

    • No. In planet of the apes, an experimental Alzheimers vaccine was used on a bunch of monkeys and they became intelligent, eventually learning to talk and kick our asses. I wonder when the next one is coming out. Should be pretty soon.

      Ah, here it is Dawn of the Planet of the Apes. Due in May 23rd 2014. Gotta wait another year. Bummer.

  2. I’ve no doubt that many women, for a price, would risk giving birth to a freak. That doesn’t change the fact that this would be a gross violation of bioethical standards. I can’t believe he would even suggest such a thing. Let him reconstitute a stone age rat or something, if he thinks he can do it. Just one, mind you. Wouldn’t want to risk that they’d start breeding and take over NYC. Of course, if that one could interbreed with existing rats … ugh. Let’s hope it all stays in the realm of scifi where it belongs.

    • Yes, that’s what I thought also. Which is why I was surprised he would suggest something like this openly. I mean, sure, you might say “I’d like to start experimenting with people and see what happens,” but for most of us, saying that isn’t much of a threat. For THIS guy, it’s kind of disturbing. And the fact that he would make this statement to the press shows a certain… lack of understanding for how the public might perceive the overall concept of human experimentation. That lack of understanding hints at a complete lack of care, meaning, I have no fricken clue what goes on in that dude’s lab.

      I thought scientists went to Argentina if they wanted to do stuff like this?

  3. Look around us, I’m not sure they have completely died out! Seriously though, this is kinda messed up. Genetic research is great when it helps cure disease. I’m not really sure I see any benefit here.

    • There could well be benefits – something along the lines of research into genes that could code for protein modifications that could result in cures for diseases. Maybe Neanderthals didn’t have diabetes, why? Maybe they never had cancer (unlikely, but still). Maybe they never got Alzheimers. We don’t know enough about what those genes code for.

      But, yeah, experimenting with humans to find out is, well, it’s completely against bioethics. You don’t talk about doing shit like this. You do it in secret, and then destroy the evidence. Damn, I feel another novel coming on. But really, why not start with all the extinct species first? I suspect it’s because Neanderthals are another intelligent species, and so closely related to humans that we could learn something from them. Plus, it’s a lot more newsworthy than bringing back a sea cow.

  4. I smell a reality show.

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